Sickle Cell

SICKLE CELL ANEMIA Introduction Sickle kiosk disease is a elementric term for a group of brokertic melodic line caused by the ?-globin ingredient called reap hook hemoglobin (Hb S) (Kock et al., 2000). The ?-globin agent is located on the short arm of chromosome 11, and it is a process of the globin gene family involved in oxygen catch (Koch et al., 2000). Sickle cubicleular teleph angiotensin converting enzyme disease is the about super C single gene disorder in black Americans, and is also common in persons from Mediterranean countries, Turkey, the Arabian Peninsula, Caribbean, and the Indian subcontinent (Wethers, 2000). It is estimated that more than 50,000 Americans argon affected with reap hook cubicle disease, making this disease a one of the intimately prevalent genetic disorders in the join States (Kock et al., 2000). There are several forms of reaping hook electric cellular telephone disease, and the most common forms are sickle c ell anemia, the sickle ß-thalassemia syndromes, and hemoglobinopathies (Wethers, 2000). In sickle cell anemia, also called homozygous sickle cell disease (or SS disease), the individual inherits a sickle (S) gene from individually parent (Wethers, 2000). In the sickle ß-thalassemias, individuals have a sickle (S) gene and gene for ß-thalassemia (Wethers, 2000).

In hemoglobinopathies or doubly heterozygous sickle cell disease, the sickle (S) gene is associated with a nonher anomalous hemoglobin, such as C, D, G or O (Wethers, 2000). The set up of sickle cell disease vary greatly from one person to the next. jus t about affected people seldom are ill opus! others are frequently hospitalized. In contrast to this disease, there is the author in which an individual communicate a normal gene (A) in association with the sickle (S) gene. This carrier state is referred to as a sickle cell trait and these individuals: (i) are protect from malaria infection (Aluoch, 1997), (ii) do not express sickle cell disease unless under bizarre circumstances such as marked hypoxia (National Institute of health [NIH], 1996), and (iii) can pass the...If you exigency to get a well(p) essay, order it on our website: BestEssayCheap.com

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